Our Funded Research Projects
Updated September 2023
| Title | Principal Investigator / Supervisor | Program Sort descending | Project Start Date | Project End Date | Total $ Awarded |
|---|---|---|---|---|---|
| Design and implementation of circulatory oxygen therapeutics derived from human hemoglobin by improved systematic chemical coupling and cross-linking | Principal Investigator: KLUGER, Ronald Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $192,039.00 | ||
| Defining disease mechanisms in Immune Thrombocytopenia (ITP) and their association with clinical outcomes | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: COOK, Richard J., NAZY, Ishac |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $317,469.00 | ||
| Improving the cryostorage of blood products using novel small molecule cryoprotectants | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: ACKER, Jason P. , ALLAN, David S. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $384,180.00 | ||
| Release, delivery and cell programming effects of platelet microparticles and microRNAs | Principal Investigator: PROVOST, Patrick Co-Investigator(s) / Trainee: BOILARD, Eric |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $427,422.00 | ||
| Polymer-based manufacturing tolerogenic miRNA-based therapeutics | Principal Investigator: SCOTT, Mark Co-Investigator(s) / Trainee: HORWITZ, Marc S. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $491,125.00 | ||
| Small molecule inhibitors of phagocytosis as replacement therapy for IVIG | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: KOTRA, Lakshmi, P. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $230,000.00 | ||
| Microfluidic devices to measure the deformability of stored red blood cells | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: SCOTT, Mark D. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $398,301.00 | ||
| Aneurysmal SubArachnoid Hemorrhage - Red blood cell transfusion And outcome (SAHaRA): a pilot randomized controlled trial | Principal Investigator: ENGLISH, Shane Co-Investigator(s) / Trainee: McINTYRE, Lauralyn A. , ALGIRD, Almunder , BOUTIN, Amélie , CHASSE, Michael , DOWLATSHAHI, Dariush , FERGUSSON, Dean A. , GRIESDALE, Donald , KRAMER, Andreas H. , LAUZIER, François , LUM, Cheemun , MARSHALL, Shawn C. , PAGLIARELLO, Giuseppe , SINCLAIR, John , TINMOUTH, Alan T. , TURGEON, Alexis F. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $157,172.00 | ||
| Development of novel blood vessel and organ sealants for blood conservation in surgical practice | Principal Investigator: BROOKS, Don Co-Investigator(s) / Trainee: DU, Caigan , HSIANG, York N. , KIZHAKKEDATHU, Jayachandran N. , KO, Frank K. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $240,996.00 | ||
| Understanding transcriptional and epigenetic control by Gfi1b towards the development of a therapy for sickle cell disease | Principal Investigator: TRUDEL, Marie Co-Investigator(s) / Trainee: MOROY, Tarik |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $453,132.00 | ||
| Myocardial Ischemia and Transfusion. The MINT rollover trial | Principal Investigator: HEBERT, Paul Co-Investigator(s) / Trainee: CARSON, Jeffrey L., DEVEREAUX, Philip J., EIKELBOOM, John W., FERGUSSON, Dean A., GOODMAN, Shaun G. , MCALISTER, Finlay A. , TINMOUTH, Alan T. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $140,210.00 | ||
| Platelet microRNAs during storage under blood bank conditions | Principal Investigator: PROVOST, Patrick Co-Investigator(s) / Trainee: HITZLER, Walter |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $349,548.00 | ||
| Pathogenesis and treatment of immune thrombocytopenia: Are there fundamental differences between anti-GPlba- and anti-GPllbllla-mediated thrombocytopenia? | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $378,529.00 | ||
| Fetal and neonatal alloimmune thrombocytopenia: novel mechanisms and therapeutic approaches | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $471,393.00 | ||
| Transfusion of red cells in hematopoietic stem cell transplantation: The TRIST Study | Principal Investigator: TAY, Jason Co-Investigator(s) / Trainee: ALLAN, David S. , COYLE, Douglas A. , FERGUSSON, Dean A. , TINMOUTH, Alan T. , WALKER, Irwin R |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $340,817.00 | ||
| Mechanisms of antibody-independent transfusion-related acute lung injury (TRALI) | Principal Investigator: KUEBLER, Wolfgang Co-Investigator(s) / Trainee: SEMPLE, John W. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $328,712.00 | ||
| Novel mechanisms of platelet aggregation: Roles of non-classical beta-3 integrin ligands and fibronectin in thrombosis and hemostasis | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $398,871.00 | ||
| Transfusion-related Epstein-Barr Virus (EBV) infection among allogeneic stem cell transplant pediatric recipients: A multicenter prospective cohort study (TREASuRE Study) | Principal Investigator: TROTTIER, Helen Co-Investigator(s) / Trainee: ALFIERI, Carolina , BUTEAU, Chantal , DUVAL, Michel , LACROIX, Jacques , ROBITAILLE, Nancy , SPINELLA, Philip , TUCCI, Marisa |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $519,766.00 | ||
| Short and long-term clinical effects of blood donor characteristics in transfusion recipients | Principal Investigator: FERGUSSON, Dean Co-Investigator(s) / Trainee: ACKER, Jason P., CHASSÉ, Michael, ENGLISH, Shane, FORSTER, Alan, KNOLL, Greg, McINTYRE, Lauralyn A., SHEHATA, Nadine , van WALRAVEN, Carl, WILSON, Kumanan , TINMOUTH, Alan T. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $103,806.00 | ||
| Process evaluation of the Canadian Blood Services' cord blood bank: managerial and donor perspectives | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: HAW, Jennie |
CIHR Health System Impact Fellowship | $46,500.00 | ||
| Options for increasing plasma supply in Canada: A health economic preference and modelling study | Principal Investigator: HOLLOWAY, Kelly Co-Investigator(s) / Trainee: KENNEDY, Kevin |
CIHR Health System Impact Fellowship | $108,500.00 | ||
| Leveraging equity-focused implementation science to evaluate and support the re-integration of men who have sex with men into the blood donation system | Principal Investigator: GOLDMAN, Mindy Co-Investigator(s) / Trainee: VESNAVER, Elisabeth |
CIHR Health System Impact Fellowship | $108,500.00 | ||
| Elianna Saidenberg Transfusion Medicine Trainee | Principal Investigator: LAU, Wendy Co-Investigator(s) / Trainee: TORDON, Bryan |
Elianna Saidenberg Transfusion Medicine Traineeship Award | $210,000.00 | ||
| Elianna Saidenberg Transfusion Medicine Trainee | Principal Investigator: LAU, Wendy Co-Investigator(s) / Trainee: VANDERMEULEN, Heather |
Elianna Saidenberg Transfusion Medicine Traineeship Award | $210,000.00 | ||
| Elianna Saidenberg Transfusion Medicine Trainee | Principal Investigator: SHIH, Andrew Co-Investigator(s) / Trainee: TAPLEY, Laura |
Elianna Saidenberg Transfusion Medicine Traineeship Award | $105,000.00 | ||
| Elianna Saidenberg Transfusion Medicine Trainee | Principal Investigator: ZELLER, Michelle Co-Investigator(s) / Trainee: GABARIN, Nadia |
Elianna Saidenberg Transfusion Medicine Traineeship Award | $210,000.00 | ||
| Elianna Saidenberg Transfusion Medicine Trainee | Principal Investigator: LIN, Yulia Co-Investigator(s) / Trainee: ARYA, Sumedha |
Elianna Saidenberg Transfusion Medicine Traineeship Award | $210,000.00 | ||
| Anti-GPIb mediated thrombocytopenia: implications for IVIG and other therapies | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: XU, Miao |
Graduate Fellowship Program | $52,000.00 | ||
| New solution for cord blood unit preservation | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: KAUSHAL, Richa |
Graduate Fellowship Program | $116,500.00 | ||
| Investigation of pathophysiology, prevention and treatment of murine Transfusion Related Acute Lung Injury (TRALI) | Principal Investigator: SEMPLE, John Co-Investigator(s) / Trainee: McVEY, Mark |
Graduate Fellowship Program | $52,000.00 | ||
| Transcriptome analyses of Staphylococcus aureus grown in platelet concentrates with focus on virulence | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: DA SILVA PAREDES, Carina |
Graduate Fellowship Program | $122,000.00 | ||
| Improving pathogen inactivation: the dengue virus-induced platelet proteome | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: TEGEGN, Tseday Zewdu |
Graduate Fellowship Program | $104,000.00 | ||
| Assessing the relationship between red blood cell deformability and transfusion lifetime | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: LAMOUREUX, Erik |
Graduate Fellowship Program | $52,000.00 | ||
| Towards the impact of protein synthesis in human platelets to transfusion medicine | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: BOSGOED, Christa |
Graduate Fellowship Program | $92,000.00 | ||
| Investigating the mechanism of anti-CD44 antibody amelioration of IVIg-treatable disease | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NORRIS, Peter |
Graduate Fellowship Program | $112,333.33 | ||
| Studying and alleviating the effects of platelet microparticles induced by pathogen reduction of platelet concentrates | Principal Investigator: PROVOST, Patrick Co-Investigator(s) / Trainee: LAUGIER, Jonathan |
Graduate Fellowship Program | $52,000.00 | ||
| Replacement of IVIg by small molecule inhibitors of phagocytosis | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: LORIAMINI, Melika |
Graduate Fellowship Program | $112,333.00 | ||
| Role of skin disinfection and buffy coat platelet production on residual bacterial contamination in platelet concentrates and cord blood stem cells | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: TAHA, Mariam |
Graduate Fellowship Program | $92,000.00 | ||
| Monoclonal antibodies with anti-D like activity in amelioration of murine ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: KHAN, Ramsha |
Graduate Fellowship Program | $56,166.67 | ||
| MRI guided focused ultrasound facilitated IVIg immunotherapy as a therapeutic approach for Alzheimer's disease | Principal Investigator: AUBERT, Isabelle Co-Investigator(s) / Trainee: DUBEY, Sonam |
Graduate Fellowship Program | $100,000.00 | ||
| Synthesis and live cell imaging of ice recrystallization inhibitors in red blood cells | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: MCMUNN, Leah |
Graduate Fellowship Program | $112,333.00 | ||
| Studies on the development of biocompatible antimicrobial platelet storage devices | Principal Investigator: BROOKS, Don Co-Investigator(s) / Trainee: HADJESFANDIARI, Narges |
Graduate Fellowship Program | $96,000.00 | ||
| Synthesis of carbohydrate derivatives for the improvement of red blood cell storage | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: MEYER, Julia |
Graduate Fellowship Program | $79,500.00 | ||
| Investigating a new class of small molecule ice recrystallization inhibitors for red blood cell cryopreservation | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: AMPAW, Anna |
Graduate Fellowship Program | $112,333.33 | ||
| Cellular therapy to improve CD4+ T-Cell responses in humanized mice infected with HIV-1: adoptive transfer of CD4+ T-cells lacking s-Src activity | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: McCARTHY, Stephen |
Graduate Fellowship Program | $96,000.00 | ||
| Defining the stem cell regulatory functions of GAS6 and FTO | Principal Investigator: MAGANTI, Harinad Co-Investigator(s) / Trainee: PASALA, Ajay |
Graduate Fellowship Program | $52,000.00 | ||
| A novel clot-dissolving agent derived from clotting factor Va | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: LEE, Frank |
Graduate Fellowship Program | $39,500.00 | ||
| Novel cell-surface engineering methods to increase immune-tolerance of allogenic cell transplantation | Principal Investigator: KIZHAKKEDATHU, Jayachandran Co-Investigator(s) / Trainee: MOON, Haisle |
Graduate Fellowship Program | $90,333.33 | ||
| The in vivo effects of liposome treatment on minimizing membrance injury in rat red blood cells during hypothermic storage | Principal Investigator: HOLOVATI, Jelena Co-Investigator(s) / Trainee: da SILVIERA CAVALCANTE, Luciana |
Graduate Fellowship Program | $100,000.00 | ||
| Modified platelet storage containers to improve quality during storage | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: PEREYRA DOS SANTOS, Nicolas |
Graduate Fellowship Program | $52,000.00 |